THE EXCRETION OF 17-KETOSTEROIDS: II. VALUES IN SEVERAL ENDOCRINE DISTURBANCES

Publisher Website
Google Scholar
Abstract
FOR the estimation of urinary 17-ketosteroids a relatively simple laboratory method is available (1), for which some normal values have been previously recorded (2). Since most, if not all, of these products are believed to be metabolites of androgenic hormones presumably elaborated only by the adrenal cortex and the gonad, their daily excretion in urine, compared with that of normal subjects in relation to sex and age, may reflect in some measure the functional status of the adrenal cortex. High values suggest hyperfunction and low values hypofunction. It is our purpose to present the values for urinary 17-ketosteroids which were obtained in a series of patients, each one of whom had an endocrine disorder. MATERIALS AND METHODS All the subjects studied were patients on the wards of the New York Medical College, Metropolitan Hospital Research Unit, and the Flower and Fifth Avenue Hospitals, who were suffering from one of a variety of endocrine conditions.