Patterns in Clinical Chemistry: Low Serum Sodium and Chloride in Hospitalized Patients

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Abstract
Based on studies of 7695 determinations of serum electrolytes at the University of Missouri, 1697 from the University of Vermont, and 1000 previously published from the Medical College of South Carolina, hospitalized patients seem to have serum sodium and chloride concentrations which are substantially lower than those of healthy individuals. Low sodium with low chloride is the commonest abnormal pattern seen in hospitalized patients. Thirty-eight possible patterns did not occur or were rare. This information can be used to enhance computer mediated laboratory quality control systems. The observations also relate to basic pattern recognition problems.

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