Pattern searching/alignment with RNA primary and secondary structures: an effective descriptor for tRNA
- 1 January 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 6 (4) , 325-331
- https://doi.org/10.1093/bioinformatics/6.4.325
Abstract
A convenient pattern-matching program using primary and higher-order structural features has been developed based on a ‘backtracking’ algorithm. A second implementation of the algorithm uses descriptors of structural features (including primary sequences) to align a list of homologous or highly similar sequences. An application of the pattern matcher to the search for tRNA and group I intron structural motifs in sequence data banks is presented. The design of a highly discriminate tRNA motif common to all cellular tRNAs and not found in a control sequence bank, was accomplished using the pattern matcher in conjunction with the alignment program.This publication has 5 references indexed in Scilit:
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