The quantitative separation on the micro-scale of phenylarsenious acid, phenylarsonic acid, arsenious acid and arsenic acid in simple solution and in urine

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Abstract
A method has been developed whereby the amts. of each constituent of a mixture of phenylarsenious acid, phenylarsonic acid, arsenious acid and arsenic acid can be determined. The acidified solution is extracted in a separatory funnel with ether and then with 0.4% ethane [long dash]1:2 dithiol in CCl4, thus extracting phenylarsenious acid and arsenious acid separated. The soln. was then reduced by the addition of KI with Na metabisulphite or l-ascorbic acid and the extraction procedures repeated to give the arsenic corresponding to phenylarsonic acid and arsenic acid. In urine dialysates both phenylarsonic acid and arsenic acid yielded ether-soluble complexes with urine constituents. This was controlled by subjecting a portion of the sample to immediate reduction to break down the complexes.