The Protein Concentration in the Proximal Tubule of the Dog*

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Abstract
Albumin and gamma globulin concentrations have been estimated in 38 samples of proximal tubule fluids from five dogs using a quantitative gel diffusion precipitin technique. Eighteen samples had albumin concentrations in the range of 2 to 8 mg/100 ml. Another 18 samples had no detectable precipitin level and were therefore less than 2-6.9 mg/100 ml. Two samples had 10 and 15 mg/100 ml of both albumin and gamma globulin. All other samples gave no gamma globulin precipitin line. Three samples tested by the hemagglutination inhibition technique had albumin concentrations in the same range as above. Albumin concentration did not change according to any pattern when plotted as a function of distance along the tubule.