Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?

This publication has 18 references indexed in Scilit:

• Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine: identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns
  Chemico-Biological Interactions, 1998
• Oxidation of Caffeine to Theobromine and Theophylline Is Catalyzed Primarily by Flavin-Containing Monooxygenase in Liver Microsomes
  Biochemical and Biophysical Research Communications, 1997
• The use of caffeine as a metabolic probe for human drug metabolizing enzymes
  General Pharmacology: The Vascular System, 1996
• Caffeine as a metabolic probe: a comparison of the metabolic ratios used to assess CYP1A2 activity.
  British Journal of Clinical Pharmacology, 1995
• Porphyrin π-cation and protein radicals in peroxidase catalysis and inhibition by anti-thyroid chemicals
  Xenobiotica, 1995
• Placental peroxidase—Further purification of the enzyme and oxidation of thiobenzamide
  Placenta, 1993
• The use of caffeine for enzyme assays: A critical appraisal
  Clinical Pharmacology & Therapeutics, 1993
• Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites
  Pharmacogenetics, 1992
• Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1
  Pharmacogenetics, 1992
• Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities
  Clinical Pharmacology & Therapeutics, 1991