A study of acetic acid production by immobilizedAcetobacter cells: Product inhibition effects

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Abstract
Acetobacter living cells were immobilized by adsorption onto a ceramic support. The effects of acetic acid inhibition have been studied in a fixed-bed pulsed-flow reactor. Provided that sufficient oxygen was available, the concentration of acetic acid was found to be independent of the flow rate. Damped oscillations of acetic acid concentration were observed after step changes in dilution rate. The theoretical model developed from steady-state data was successful in predicting the experimental dynamic behavior of the reactor.