Nickel-catalyzed asymmetric α-arylation of ketone enolates
- 21 February 2006
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 13,p. 1413-1415
- https://doi.org/10.1039/b601691j
Abstract
An atropisomeric dipyridyldiphosphine, P-Phos, can effect highly enantioselective Ni-catalyzed α-arylation of ketone enolates with aryl halides to install an all-carbon quaternary stereogenic center in up to 98% ee and excellent yields.Keywords
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