Liquid Chromatographic Analysis of Some N-Alkyl-3,4-methylenedioxyamphetamines
- 1 September 1987
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 10 (11) , 2497-2504
- https://doi.org/10.1080/01483918708068930
Abstract
The liquid chromatographic separation of a series of low molecular weight N-alkyl derivatives of 3,4-methylenedioxyamphetamine (MDA) is reported. The N-methyl-, N-ethyl- and N,N-dimethyl-derivatives of MDA have appeared as street drugs in recent years. These compounds are becoming significant forensic problems due to their unique pharmacological properties and relative ease of chemical synthesis. These amines were synthesized via reductive amination of the corresponding ketone with alkylamines. The UV absorption spectra for these compounds produced almost equally intense absorbance at 234 and 285 nm. The compounds were separated by reversed-phase (C18) HPLC procedures using a mobile phase of aqueous methanol at low pH.This publication has 5 references indexed in Scilit:
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