POST‐KALA‐AZAR DERMAL LEISHMANIASIS IN THE SUDAN: PERIPHERAL NEURAL INVOLVEMENT

Publisher Website
Google Scholar
Abstract
Four patients developed post‐kala‐azar dermal leishmaniasis and neuritis (PKDL) 1 to 6 months following apparently successful treatment of kala‐azar. The duration of the lesion varied between 1 month and nearly 5 years. The lesions were macules, papules, or nodules affecting the face, extremities, and trunk. The diagnosis was made by demonstration of the parasite in slit smear and biopsies and by a positive direct agglutination test (DAT). Histologically, the patients were found to have neuritis affecting the cutaneous nerves in the lesion only. The nerves showed a lymphohistiocytic infiltration and occasionally parasites. There was no impairment of sensation. Response to sodium stibogluconate was good. PKDL may simulate leprosy both clinically and pathologically.

This publication has 6 references indexed in Scilit: