Studies in avian carbohydrate metabolism

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Abstract
The decrease in respiration rate in minced avian brain systems is substantially reduced in presence of lactate. It is not reduced by galactose, mannitol, Na [beta]-glycerophosphate, hexosedi- and hexosemono-phosphates. The last 2 substrates may influence the rate of fall initially. Na pyro-phosphate added alone has little influence upon maintenance of respiration in the surviving tissue. Added with lactate, it much increases the respiration rate, values considerably in excess of those with lactate alone being obtained. Lactate and pyrophosphate are essential constituents of the respiration system. [alpha]-Glycerophosphate has a remarkable additional influence. Ringer-phosphate to which lactate, pyrophosphate and [alpha]-glycerophosphate have been added gives much better maintenance than lactate alone. Exps. with fluoride indicate that survival respiration in lactate-phosphate soln. involves in part a hexosephosphate stage.