EFFECT OF CORTISOL ON GROWTH AND URIC ACID EXCRETION IN THE CHICK

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Abstract
SUMMARY: Metabolic effects of various doses of cortisol were studied in the young male chick. Inhibition of body growth increased with dose but there was no proportional decrease in food intake. Liver weight and uric acid excretion increased similarly with dose. When the temporal relationships of these effects were compared, there was no correlation between the increase in uric acid excretion and the increase in liver weight. It is therefore concluded that the increase in liver weight and uric acid excretion are not linked to a common effect of cortisol. Liver glycogen deposition was more sensitive to cortisol compared with the other effects.