THE DELETERIOUS EFFECT IN DOGS OF A DRY PROTEIN RATION 1
Open Access
- 1 September 1944
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 23 (5) , 816-823
- https://doi.org/10.1172/jci101555
Abstract
Dry protein in small amts. (1.5 gm./kgm.) without water maintains dogs in N equilibrium without change in the N excretion. Larger amts. of protein (2-7.2 gm./kgm.) increase the metabolism of protein and the nitrogenous end-products in the urine. The increased excretion of N necessitates a large urine volume, even when dehydration is present. Dry protein in amts. greater than that necessary for N equilibrium, without adequate supplies of water, increases dehydration and decreases survival time. Similar amts. of protein with an adequate intake of water (whole fish) will maintain dogs in an excellent condition for at least 4 weeks.) In the dog, administration of carbohydrate can conserve water. The economy of body water results chiefly from a decrease in protein metabolism and in the amt. of N necessitating excretion. In addition, the water of oxidation of the carbohydrate is made available.This publication has 5 references indexed in Scilit:
- ELECTROLYTE AND FLUID STUDIES DURING WATER DEPRIVATION AND STARVATION IN HUMAN SUBJECTS, AND THE EFFECT OF INGESTION OF FISH, OF CARBOHYDRATE, AND OF SALT SOLUTIONS 12Journal of Clinical Investigation, 1944
- EXPERIMENTAL HYPERTONICITY: ALTERATIONS IN THE DISTRIBUTION OF BODY WATER, AND THE CAUSE OF DEATH 1Journal of Clinical Investigation, 1944
- PLASMA VOLUME OF DOGS IN DEHYDRATION, WITH AND WITHOUT SALT LOSS 1Journal of Clinical Investigation, 1943
- PROLONGED WATER DEPRIVATION IN THE DOG 1Journal of Clinical Investigation, 1942
- EXPERIMENTAL HYPOSTHENURIA 12Journal of Clinical Investigation, 1939