Percutaneous edge‐to‐edge mitral valve repair: 2‐year follow‐up in the first human case

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Abstract
We report the first‐in–human mitral valve repair using percutaneous technology that creates a “surgical‐like” edge‐to‐edge repair. A catheter‐delivered clip was introduced transseptally from the femoral vein, advanced through the mitral orifice, retracted to grasp the leaflets, and detached to create a functional double‐orifice valve. The patient had an uncomplicated post‐procedural course. Echocardiography at 1‐ and 2‐years post procedure showed mild mitral regurgitation and positive ventricular remodeling. The success of this case suggests that percutaneous mitral valve repair may be a feasible therapy for certain patients suffering from mitral regurgitation.