A Comparative Study of Thiamine-sparing Agents in the Rat
- 1 March 1957
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 61 (3) , 421-436
- https://doi.org/10.1093/jn/61.3.421
Abstract
The effects of thiamine, fat, protein, penicillin and ascorbic acid, singly and in combination in the diet, on the growth of rats were studied. The effects of these agents on thiamine concentration of tissues were determined. Fat or protein, penicillin, and ascorbic acid were effective sparing agents in combination. Penicillin plus streptomycin or aureomycin was no more effective than penicillin alone. All 4 sparing agents increased the thiamine content of the animals in approximate proportion to their effects on growth.Keywords
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