Abstract
Intraven. isoniazid has little parasympathetic blocking, sympathetic stimulating, or other general pharmacodynamic properties on exptl. animals. Respiration, metabolic rate, systemic blood pressure, and heart rate were not affected in the dog by doses of isoniazid corresponding to human daily oral doses. Similar results were obtained with iproniazid, except that transient hypotension and tachycardia were seen.