THE NOSOLOGIC SITUATION OF THE LANDRY-GUILLAINBARRE SYNDROME

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Abstract
Five case reports of patients exhibiting a combination of signs and symptoms suggesting acute involvement of both the central and the peripheral nervous systems belonging to the group that has been called the Landry-Guillain-Barre syndrome have been presented. It is suggested that the hyperalbuminosis of spinal fluid is the result of the increased activity of the Schwann cells during the stage of regeneration of the peripheral nerves. It is suggested that the Guillain-Barre" syndrome represents one end of a spectrum of conditions in which the nervous system is the site of an antigen-antibody reaction following a viral infection, the other end of the spectrum being represented by post-infectious encephalomyelitis. The authors feel that the eponymic designation "Guillain-Barrfi syndrome" or "Landry-Guillain-Barre syndrome" be abandoned and replaced by the term post-infectious radiculoneuropathy.

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