Symptomatic Therapy in Viral Illness

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Abstract
The ability to perform sustained nonphysical work is diminished during acute infectious illnesses. In this study, anticipated decrements in work performance did not occur when volunteers with experimentally induced sandfly fever were given symptomatic therapy. The therapeutic regimen, which included aspirin and propoxyphene hydrochloride administered every four hours for two days, did not entirely relieve fever or the symptoms of illness. This regimen had no detectable effect on the work performance of other noninfected volunteers included in the study as therapy controls. (JAMA228:581-584, 1974)

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