CARDIOPULMONARY MANIFESTATIONS OF SYSTEMIC LUPUS-ERYTHEMATOSUS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 5  (3) , 299-306
Abstract
Of 17 patients with systemic lupus erythematosus participating in a controlled prospective study, 9 (52%) had maximal mid-expiratory flow rates suggesting of obstructive or obstructive and restrictive pulmonary disease. Cigarette smokers with systemic lupus erythematosus had significantly lower (P < .05) maximal mid-expiratory flow rates than either non-smokers with systemic lupus erythematosus or smokers with degenerative joint disease. Echocardiography showed pericardial thickening in 6 patients (41%) and mitral valvular abnormalities in 4 (24%) patients. Echocardiography was an effective means of detecting pericardial disease in patients with systemic lupus erythematosus.

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