Coexpression of Genetically Engineered Fused Enzyme between Yeast NADPH–P450 Reductase and Human Cytochrome P450 3A4 and Human Cytochrome b5 in Yeast
- 1 September 2000
- journal article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 381 (1) , 164-170
- https://doi.org/10.1006/abbi.2000.1953
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Cooperativity in Oxidations Catalyzed by Cytochrome P450 3A4Biochemistry, 1997
- Kinetic Studies on a Genetically Engineered Fused Enzyme between Rat Cytochrome P4501A1 and Yeast NADPH-P450 ReductaseBiochemistry, 1994
- Human cell lines, derived from AHH-1 TK+/− human lymphoblasts, genetically engineered for expression of cytochromes P450Toxicology, 1993
- Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5Gene, 1993
- Role of phospholipids in reconstituted cytochrome P 450 3A form and mechanism of their activation of catalytic activityBiochemistry, 1992
- The role of cytochrome b5 in adrenal microsomal steroidogenesisThe Journal of Steroid Biochemistry and Molecular Biology, 1992
- Genetically Engineered Modification of P450 Monooxygenases: Functional Analysis of the Amino-Terminal Hydrophobic Region and Hinge Region of the P450/Reductase Fused EnzymeDNA, 1988
- The complete nucleotide sequence of human liver cytochrome b5 mRNABiochemical and Biophysical Research Communications, 1988
- Rabbit liver cytochrome P-450 LM2: roles of substrates, inhibitors, and cytochrome b5 in modulating the partition between productive and abortive mechanismsBiochemistry, 1987
- Expression of Rat NADPH-Cytochrome P-450 Reductase cDNA inSaccharomyces cerevisiaeDNA, 1986