A qualitative comparison of protein synthesis in the preimplantation embryos of four rodent species (mouse, rat, hamster, gerbil)

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Abstract
An examination of the protein profiles obtained from preimplantation embryos of mouse, rat, hamster, and gerbil revealed marked species differences in the one‐cell fertilized eggs but a striking similarity in the major proteins produced by blastocysts. The early change in protein profile observed in all four species suggests that activation of the embryonic genome before the second cleavage division is a rodent characteristic. The initial marked species differences resulting from putative maternal transcripts could be important in the establishment and maintenance of species integrity.