Calcitonin stimulates glycogenolysis in the liver of fasted rats.
- 1 January 1981
- journal article
- research article
- Published by Japan Endocrine Society in Endocrinologia Japonica
- Vol. 28 (5) , 643-646
- https://doi.org/10.1507/endocrj1954.28.643
Abstract
The effect of calcitonin (CT) on glycogenolysis in the liver was investigated in fasted rats. The fasting produced a marked decrease in the hepatic glycogen content. Thyroparathyroidectomy (TPTX) significantly prevented the decline in hepatic glycogen by fasting as compared with sham operation. This prevention by TPTX was clearly relieved by s.c. CT administration (80 MRC [Metabolic Research Council] mU/100 g body wt). The appreciable effect of the hormone was also observed at doses of 20 and 40 MRC mU CT/100 g body wt. Evidently, CT plays a physiological role in the stimulation of hepatic glycogenolysis after fasting in rats.This publication has 3 references indexed in Scilit:
- Calcitonin increases serum glucose concentration independently of insulin secretion in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1981
- Effects of calcitonin and epinephrine on serum glucose concentration in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1980
- Effect of calcitonin on serum glucose concentration in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977