Chromosome size polymorphism inPlasmodium falciparumcan involve deletions of the subtelomeric pPFrep20 sequence
- 1 January 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 16 (10) , 4331-4340
- https://doi.org/10.1093/nar/16.10.4331
Abstract
The P. falciparum pPFrep20 repetitive element from the Palo Alto Uganda strain ahs been isolated and sequenced. The Palo Alto pPFrep20 repeat (pPFPArep20) has a clustered subtelomeric location and on chromosome 1 has been deleted from one end. Analysis of chromosome 1 from 5 other strains has revealed that pPFrep20 sequences have been deleted form one end in 3 of them. Thus, deletion of pPFrep20 appears to be a frequent event that could significantly contribute to chromosome size polymorphism in P. falciparum.This publication has 21 references indexed in Scilit:
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