Chromosome 1 abnormalities in relapse and terminal stages in childhood leukemia
- 1 January 1979
- journal article
- research article
- Published by Wiley in Medical and Pediatric Oncology
- Vol. 7 (1) , 9-16
- https://doi.org/10.1002/mpo.2950070103
Abstract
Seven of 114 children with leukemia were shown to have abnormalities of chromosome 1. These included trisomy of parts of chromosome 1 as well as translocations of chromosome 1 to other chromosomes. The abnormalities were found during a relapse or terminal stage, after which the patient was refractory to therapy in all cases.Keywords
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