ON THE RELATION OF THE ORGANISMS IN THE TUNICA VAGINALIS OF ANIMALS INOCULATED WITH MEXICAN TYPHUS TO RICKETTSIA PROWAZEKI AND TO THE CAUSATIVE AGENT OF THAT DISEASE
Open Access
- 1 February 1930
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 51 (2) , 189-207
- https://doi.org/10.1084/jem.51.2.189
Abstract
Healthy lice became infected with Rickettsia prowazeki after feeding on monkeys inoculated with a strain of Mexican typhus. The same result was obtained in 100% of lice by rectal inoculation of an emulsion of tunica vaginalis of guinea pigs reacting to the same strain. In the tunica vaginalis of guinea pigs and rats inoculated intraperitoneally with an emulsion of lice containing R. prowazeki the intracellular organism constantly associated with the passage strain appeared regularly. R. prowazeki found in lice and the organism constantly present in the tunica of guinea pigs and rats reacting to the author''s strain of tabardillo are indistinguishable morphologically and tinctorially and their mode of intracellular multiplication is alike in every respect. It is concluded that they are identical. This organism is constantly associated with the causative agent of Mexican typhus, both in mammals and in lice, and all attempts to separate them have failed.Keywords
This publication has 6 references indexed in Scilit:
- Public Health Weekly Reports for AUGUST 9, 1929.1929
- Tabardillo, An American Variety of TyphusThe Journal of Infectious Diseases, 1929
- Endemic Typhus Fever of the Southeastern United States: Reaction of the Guinea PigPublic Health Reports®, 1929
- Experiments Relating to the Pathology and the Etiology of Mexican Typhus (Tabardillo): 1. Clinical Course and Pathologic Anatomy of Tabardillo in Guinea-PigsThe Journal of Infectious Diseases, 1928
- EXPERIMENTAL STUDIES ON THE ETIOLOGY OF TYPHUS FEVERThe Journal of Experimental Medicine, 1922
- Public Health Weekly Reports for MAY 31, 1912.1912