STUDIES ON THE RENAL CONCENTRATING MECHANISM. III. EFFECT OF HEAVY EXERCISE

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Abstract
Heavy exercise causes impairment of concentrating ability and a decrease in creatinine and mannitol clearance in hydropenic men who are studied without prior solute loading or during a small mannitol diuresis. During a large mannitol diuresis there is no distinct change in concentrating ability or in creatinine and mannitol clearance with exercise. In all 3 groups exercise causes an abrupt decrease in total solute excretion and particularly in Na excretion.