COPPER-CATALYZED REACTION OF GRIGNARD REAGENTS WITH β-PROPIOLACTONES: A CONVENIENT METHOD FOR THE SYNTHESIS OF β-SUBSTITUTED PROPIONIC ACIDS
- 5 May 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 9 (5) , 571-574
- https://doi.org/10.1246/cl.1980.571
Abstract
Grignard reagents react with β-propiolactones in the presence of a copper(I) catalyst to give β-substituted propionic acids in high yields.Keywords
This publication has 7 references indexed in Scilit:
- Action d'organolithiens et organomagnésiens sur la propiolactone en présence de sel cuivreux synthèse d'acides carboxyliquesTetrahedron Letters, 1980
- Conjugate addition of Grignard reagents to ethyl acrylateThe Journal of Organic Chemistry, 1977
- Prescriptions and Ingredients for Controlled CC Bond Formation with Organometallic Reagents. New synthetic methods (5)Angewandte Chemie International Edition in English, 1974
- Halopolycarbon homologationJournal of the American Chemical Society, 1974
- Copper-catalyzed coupling of grignard reagents and akyl halides in tetrahydrofuran solutionsJournal of Organometallic Chemistry, 1972
- Reaction of Organometallic Compounds with PropiolactoneThe Journal of Organic Chemistry, 1963
- β-Propiolactone. VII.1 Reactions with Grignard ReagentsJournal of the American Chemical Society, 1949