Ergosterol biosynthesis inSaccharomyces cerevisiae
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 154 (3) , 269-277
- https://doi.org/10.1007/bf00571282
Abstract
Thermosensitive mutants, auxotrophic for ergosterol synthesis, have been isolated, analyzed genetically and their enzymatic deficiencies investigated. These mutants were classified into seven unlinked complementation groups. These groupes lack the following enzymatic activities: squalene epoxidase (erg 1), 2,3-oxidosqualene-lanosterol cyclase (erg 7), phosphomevalonic kinase (erg 8), mevalonic kinase (erg 12) and squalene synthetase (erg 9, erg 10, erg 11).Keywords
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