The Acetylcholine Content and Cholinesterase Activity of the Bull Retractor Penis Muscle
- 1 February 1970
- journal article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 78 (2) , 159-167
- https://doi.org/10.1111/j.1748-1716.1970.tb04651.x
Abstract
The acetylcholine content of the bull retractor penis muscle, duodenum and urinary bladder was assayed By super fusion of the eserinized frog rectos muscle. The capacity of retractor homogenates to split acetyl‐β‐methylcholine, butyrylcholine and acetylcholine was estimated with the manometric technique. The acetylcholine content of the retractor was of the same order of magnitude as that of the duodenum, but it was twice as high as the amount found in the urinary bladder. A moderate activity of acetylcholinesterase and non‐specific cholin esterase was observed. The role of acetylcholine in the function of the efferent nerve fibres running in the bull retractor is discussed. So far as the classical definitions are applied it is regarded as unlikely that it serves as a neurohumoral transmitter substance either at ganglionic synapses or at neuro effector junctions. There is as yet no conclusive explanation for the mode of action of acetylcholine in these nerve fibres.Keywords
This publication has 26 references indexed in Scilit:
- Acetylcholine in Adrenergic TransmissionAnnual Review of Pharmacology, 1965
- Sympathetic Postganglionic MechanismNature, 1959
- Butyrylcholinesterase in human and ruminant nervous tissueNeurology, 1958
- Die Cholinester der RindermilzHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1958
- The Assay of Acetylcholine on the Superfused Frog Rectus MuscleJournal of Pharmacy and Pharmacology, 1957
- Zur Frage des Vorkommens von Butyryicholin im RindergehirnHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1956
- THE TECHNIQUE OF SUPERFUSIONBritish Journal of Pharmacology and Chemotherapy, 1953
- A Method for Qimntitative Determination of Acetylcholine Precursor and Free Acetyl‐choline in Tissues.Acta Physiologica Scandinavica, 1944
- ON THE MECHANISM OF ERECTIONAmerican Journal of Physiology-Legacy Content, 1933
- On some physiological actions of ergotThe Journal of Physiology, 1906