Penicillin Treatment of Gonorrheal Urethritis

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Abstract
THE increase in the number of cases of gonorrhea failing to respond to previously effective doses of penicillin has attracted much interest in recent years.1 Although many of these failures seem to be explained by the finding of strains of Neisseria gonorrhoeae with decreased susceptibility to penicillin2 , 3 some investigators4 5 6 7 consider this explanation alone inadequate. The increase in penicillin tolerance of the gonococcus has not been very striking, and it is believed that even a moderate dose of penicillin would suffice to cure the great majority of patients even if they harbored so-called "resistant" strains.8 9 10 11 Another explanation offered for the treatment . . .

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