THE GERMICIDAL ACTION OF HALOGEN DERIVATIVES OF PHENOL AND RESORCINOL AND ITS IMPAIRMENT BY ORGANIC MATTER

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Abstract
Results of experiments on the disinfectant action of phenol, resorcinol and their halogen derivatives, against Barillus typhosus and Staphylococcus pyogenes-aureus, tend to indicate that there is a distinct relationship between constitution of these derivatives and impairment of their disinfectant action by organic matter. It is shown that even the exceedingly small quantity of organic matter in the original culture suffices to produce very considerable impairment of germicidal efficacy of certain compounds. A working hypothesis of disinfectant action is outlined, depending on the assumption of formation of so-called molecular (additive) compounds of the disinfectant agent with certain free reactive groups in the organic matter, or the protoplasm, respectively, which is to form the basis for further studies.