Cutaneous nocardiosis complicating management of Crohn's disease with infliximab and prednisone
Open Access
- 26 October 2004
- journal article
- case report
- Published by CMA Impact Inc. in CMAJ : Canadian Medical Association Journal
- Vol. 171 (9) , 1063-1064
- https://doi.org/10.1503/cmaj.1040563
Abstract
INFLIXIMAB IS A CHIMERIC ANTI-TUMOUR NECROSIS FACTOR-α antibody that is efficacious in treating Crohn9s disease. However, its immunomodulatory properties increase susceptibility to opportunistic infections. We present a case of cutaneous Nocardia infection in a patient who was taking infliximab for Crohn9s disease. The case illustrates the challenges in the diagnosis and management of this disease and serves as a reminder of the complications associated with the use of immunomodulatory agents.Keywords
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