Intra-osseous Venography with Special Reference to its Complications

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Abstract
After a survey of the technique of intra-osseous venography and the literature on its complications a series of 14 venographies performed on 13 patients with injection of 40–60 ml. of 35 per cent Umbradil into the medial malleolus is presented. The complications, which occurred with a higher frequency than might have been expected on the basis of the literature, are reviewed. Pain at the site of injection developed in all the patients; in about half of the cases the pain was intense, and in two instances it persisted for more than a month. In spite of prophylactic penicillin treatment fever developed in four patients. The venographic examination was followed by thrombophlebitis in two cases; one of these was of short duration, whereas the second persisted for several months and resulted in post-traumatic reflex dystrophy of two months' duration. Follow-up radiographs revealed slight periosteal thickening at the site of injection in three patients.

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