Efficacy of Live, Attenuated Measles-Virus Vaccine Given with Human Immune Globulin

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Abstract
MEASLES, with its serious complications, remains A one of the important diseases of childhood. Numerous past investigations have been carried out with the purpose of developing a vaccine against this disease. Most significant progress in this endeavor was made by Enders et al.,1 who grew measles virus in tissue cultures of animal cells and who attenuated the virulence of the virus for man by passage in human cell cultures, in embryonated hen's eggs and in tissue cultures of chick embryo.In susceptible children given Enders's attenuated, live measles-virus vaccine neutralizing and complement-fixing antibodies against the virus uniformly developed.2 Krugman, Giles . . .

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