Rat growth hormone gene: intervening sequences separate the mRNA regions
Open Access
- 1 January 1979
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 6 (7) , 2471-2482
- https://doi.org/10.1093/nar/6.7.2471
Abstract
Rat genomic DNA was digested with various restriction endonucleases, separated by gel electrophoresis and hybridized to 125I-labeled mRNA for the precursor protein to growth hormone. Restriction sites were found within the genomic DNA that were not found in the previously reported DNA sequence corresponding to the mRNA (19). It appears that the gene for growth hormone contains intervening sequences separating the DNA regions that specify mRNA sequences.Keywords
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