TESTOSTERONE PROPIONATE PELLET IMPLANTATION IN GYNECIC DISORDERS
- 2 January 1943
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 121 (1) , 17-24
- https://doi.org/10.1001/jama.1943.02840010019004
Abstract
The employment of so-called "male" sex hormone in the treatment of certain gynecic disorders may appear paradoxic but it is not unphysiologic. Androgenic hormones are not peculiar to the male, for they are elaborated also by the female. The Callows,1 Womack and Koch2 and others have isolated from the urine of normal women the same two androgens identified in the urine of normal males. It is reasonable to suppose that in woman's hormonal economy androgens play some physiologic role. In recent years there has been an increasing trend to use androgens in gynecologic therapy. This practice has received much support, much condemnation. The schism is wide. Two diverse opinions, each crystallized from a wealth of experience, are found in the statement of Geist and Salmon3 that "the use [of androgens] as therapeutic agents has a sound rationale" and the contention of Hamblen4 that "androgens have noThis publication has 9 references indexed in Scilit:
- CORRELATIONS BETWEEN THE CHEMICAL STRUCTURE AND THE PHARMACOLOGICAL ACTIONS OF THE STEROIDS1Endocrinology, 1942
- ANDROGEN THERAPY IN GYNECOLOGYJAMA, 1941
- CUSHING'S SYNDROME INTERPRETED AS HYPERADRENOCORTICISM LEADING TO HYPERGLUCONEOGENESIS: RESULTS OF TREATMENT WITH TESTOSTERONE PROPIONATE1Journal of Clinical Endocrinology & Metabolism, 1941
- PREVENTION OF EXPERIMENTAL UTERINE AND EXTRAUTERINE FIBROIDS BY TESTOSTERONE AND PROGESTERONE1Endocrinology, 1941
- Kidneys and Sex HormonesBMJ, 1940
- THE EFFECT OF TESTOSTERONE ON THE MONKEY UTERUS AND THE ADMINISTRATION OF STEROIDAL HORMONES IN THE FORM OF DEANESLYPARKES PELLETS1Endocrinology, 1940
- The isolation of androsterone and transdehydroandrosterone from the urine of normal womenBiochemical Journal, 1938
- REACTIONS OF THE UTERINE MUSCLE AND ENDOMETRIUM OF THE RABBIT TO TESTOSTERONEQuarterly Journal of Experimental Physiology, 1937
- THE TESTICULAR HORMONE CONTENT OF HUMAN URINE*Endocrinology, 1932