The λ phage att site: functional limits and interaction with Int protein
- 1 May 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 285 (5760) , 85-91
- https://doi.org/10.1038/285085a0
Abstract
Site-specific integrative recombination of bacteriophage λ involves unequal partners. The minimal phage att site is composed of approximately 240-base pairs and four distinct binding sites for Int protein, at least three of which are crucial for function. This ‘donor site’ recombines efficiently with a smalle ‘recipient site’ that lacks the extensive interactions with Int protein.Keywords
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