Prostaglandin E1 Versus Phentolamine/Papaverine for the Treatment of Erectile Impotence: A Double-Blind Comparison
- 1 March 1989
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 141 (3 Part 1) , 549-550
- https://doi.org/10.1016/s0022-5347(17)40889-5
Abstract
The use of intracavernous prostaglandin E1 was studied in 48 organically impotent men. Eight men with previous chemical priapism did not have chemically induced priapism at up to 4 times the minimum effective dose of prostaglandin E1. Of 15 men with arteriogenic impotence who had failed prior intracavernous phentolamine and papaverine therapy 10 had adequate erections with prostaglandin E1. A total of 25 men received intracavernous prostaglandin E1 and phentolamine plus papaverine in a double-blind fashion. Erections with prostaglandin E1 were equal or superior to those with phentolamine plus papaverine in each case.Keywords
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