Toxicological Studies on the Molt Inhibiting Insecticide (EL-494) Against the Gypsy Moth and Effect on Chitin Biosynthesis12
- 1 February 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Economic Entomology
- Vol. 73 (1) , 22-25
- https://doi.org/10.1093/jee/73.1.22
Abstract
All larval instars of Lymantria dispar (L.) were fed on treated diet containing 13 different concentrations varying from 0.0 to 2.0 ppm of EL-494 (N[[[5-(4-bromophenyl)-6-methyl-2-pyrazinyl] amino]-carbonyl]-2,6-dichlorobenzamide), a molt inhibiting insecticide, and the larvae were scored for molting abnormalities. EC50 values of EL-494 for failure to molt the 1st time were 0.39–0.88 ppm and for failure to molt a 2nd time were 0.13–0.43 ppm. The 5th and 6th instars were the most susceptible while the 1st and 2nd instars were the least susceptible. Adult emergence, especially of females, was reduced by continuous feeding on concentrations of EL-494 that did not affect the 1st and 2nd molt. The incorporation of 14C-glucose into chitin was reduced 77% relative to controls when larvae were fed on diets containing 20 ppm of EL-494.This publication has 1 reference indexed in Scilit: