Abstract
THERE is an old saying that the study of clinical dermatology is the study of gross and microscopical pathology of the skin in the living. In recent years the physiology of the skin of the human being has become better understood. As a result the practice of modern clinical dermatology has become even more exciting because it encompasses not only the understanding and correlation of gross and microscopical structural changes of the skin but also the "applied physiology" of the skin.1 When the program chairman suggested that this discussion might include some physiologic approaches to the understanding of skin disorders, . . .

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