Relationship between Electrical and Spontaneous Thrombosis

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Abstract
The triggering of electrical thrombosis on electrodes depends on the coagulation steps prior to factor IX activation. Factor XII may be responsible for this phenomenon. The platelet may also play a role. It has been shown that platelet deposition is visible at potentials more positive than +0.3 V versus the normal hydrogen electrode. The same compounds which inhibit intravascular thrombosis will also impair electrical thrombosis. * Supported in part by grants No. HE 07371, 07821 and 10795 from the National Heart Institute, National Institutes of Health, United States Public Servies, Bethesda, Maryland. 1 Department of Experimental Medicine, University College, Galway, Ireland.