Discovery of an inherited bisatellited metacentric microchromosome in amniotic cell culture
- 1 September 1979
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 16 (3) , 183-190
- https://doi.org/10.1111/j.1399-0004.1979.tb00989.x
Abstract
The identification is reported of an extra bisatellited metacentric microchromosome in amniotic cell culture from the 3rd pregnancy of an identical twin (amniocentesis being performed because of age), and its subsequent finding in the maternal parent as an inherited familial marker. The carriers of the microchromosome are all clinically normal and the parents opted for continuation of pregnancy. Only 1 other report was found of a similar microchromosome detected in amniotic fluid culture, but this may be the 1st bisatellited microchromosome to be clearly identified from an amniotic cell culture using Ag staining.Keywords
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