THE INFLUENCE OF PYLORECTOMY UPON THE STRENGTH OF THE ACID SECRETED BY THE FUNDUS

Publisher Website
Google Scholar
Abstract
An analysis of exps. performed on whole stomach pouches with and without pyloric removal and on dogs before and after partial gastrectomy shows that removal of the pylorus produces the following changes in gastric secretion: (1) A decrease in the quantity but no change in the concn. of the acid secreted by the fundus. (2) Following partial gastrectomy the gastric contents contain large amounts of a thick viscid mucus when the acid secretion is low but the mucus tends to disappear when the acid secretion is raised by histamine or the intestinal phase. This mucus is rich in neutral chloride and when present the total and neutral chloride concentration of the secretion is above normal. This mucus was not noted in whole stomach pouches from which the pylorus had been removed.

This publication has 3 references indexed in Scilit: