The Fate of Uniformly Labelled 14C Fructose in Different Parts of the Brain and the Pituitary in Goats

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Abstract
The fate of uniformly labelled 14C fructose has been studied in different parts of the brain and in the anterior and posterior pituitary. Generally, the metabolism of fructose was less than that of glucose. Particularly in the anterior part of the pituitary the fructose utilisation was small. As the oxygen consumption was little affected by the fructose, the utilisation of endogenous substances must be increased compared to experiments where glucose was used as substrate. The rate of conversion of fructose into various amino acids was considerably lower in the periventricular parts of the hypothalamus and in the anterior part of the pituitary as compared to the glucose experiments. The observed differences are discussed in relation to the importance of the pentose shunt.