On Haemoglobin Degradation in the Newborn

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Abstract
The blood of normal infants at birth contained 0.5-2.4% saturation of carboxyhemoglobin and 0-110 mg/100 ml haptoglobin. Haptoglobins were present in the cord blood of 59% (54 of 91) clinically normal neonates who did not subsequently become jaundiced, and in 31% (26 of 116) neonates who did become icteric. The development of the plasma haptoglobins during the first week of life appears not to be influenced by the presence of Rh- or immune ABO-antibodies, nor by the rate of development or degree of bilirubinemia, except in those infants with severe fetal erythroblastosis, who presented with peripheral hemoglobin levels of less than 10 g/100 ml, when the haptoglobins were consistenty absent In these anemic infants, the carboxyhemoglobin levels ranged from 0.1-2.2%.

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