The Natural History of Recurrent Optic Neuritis

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Abstract
Optic neuritis (ON) is an inflammatory demyelinating syndrome of the central nervous system. It may occur in isolation or as part of multiple sclerosis (MS) or neuromyelitis optica (NMO) (Devic disease).1 It results in loss of vision and may be associated with eye pain and color vision and visual field deficits and phosphenes. It can affect either or both eyes, sequentially or simultaneously. Optic neuritis is considered idiopathic when symptoms develop across hours to days and remit spontaneously following corticosteroid therapy and when various toxic, nutritional, metabolic, vascular, hereditary, infectious, infiltrative, autoimmune, or compressive etiologies have been excluded.2