Physiologic Aspects of Prolonged Weightlessness

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Abstract
JUST as we are accustomed to think of the physiology of exercise, we should be thinking too about the pathology of inactivity and disuse."1 For as long as man has contemplated space flight his imagination has been captured by the state of zero gravity or weightlessness. In this biologic never-never land speculation has often outstripped the collection of data. Because the zero-gravity state cannot yet be effectively created or maintained for more than brief seconds on earth the physiologic effects of prolonged weightlessness remain unknown. This essay is presented to acquaint the general medical reader with some of the speculations . . .

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