Enzymatic and hormonal responses following a 24 h endurance run and a 10 h triathlon race

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Abstract
Muscle cell leakage and hormonal changes were compared immediately after and during the 3 days following a 24 h endurance run (R24 h) in 8 subjects, and a 10 h triathlon non-competitive race (T10 h) in 6 subjects. The study showed three main differences: 1) plasma enzyme increases were considerably more significant in R24 h than in T10 h: compared with resting levels, creatine kinase increased ×120 after R24 h but only ×2 after T10 h; lactic dehydrogenase ×4, as opposed to ×1.5; and transaminases only showed an increase after R24 h. The plasma myoglobin increase after R24 h was double that found after T10 h; 2) for the same magnitude of plasma aldosterone and cortisol after R24 h and T10 h (3 times the resting levels), a highly significant decrease in urinary Na+ (p+ (p24 h; and 3) the plasma free noradrenaline level increased significantly after R24 h (×2.6) whereas it was unchanged after T10 h. In contrast, the plasma level of conjugated dopamine increased only after T10 h (×3.7, p10 h.

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