Metoprolol in anaesthesia for oral surgery

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Abstract
Summary: Metoprolol, a cardioselective beta‐adrenergic blocking drug, was given, with a placebo as an alternative, in a double‐blind trial to 60 patients who were undergoing removal of third molar teeth under general anaesthesia. Dysrhythmias occurred in significantly fewer patients in the metoprolol group than in the control group, and when ventricular dysrhythmias occurred they were abolished in every case by the administration of metoprolol. It is concluded that metoprolol is effective in preventing cardiac dysrhythmias occurring during oral surgery carried out under general anaesthesia.