Metformin: its botanical background
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Open Access
- 1 April 2004
- journal article
- research article
- Published by Wiley in Practical Diabetes International
- Vol. 21 (3) , 115-117
- https://doi.org/10.1002/pdi.606
Abstract
This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, a substance with blood glucose‐lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957. Copyright © 2004 John Wiley & Sons, Ltd.Keywords
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